Bulk Mitraphylline

Chemesis provides Mitraphylline as a premium-grade isolate for specialized scientific investigation. Unlike the primary mitragynines, Mitraphylline is a pentacyclic oxindole alkaloid that has gained significant academic interest for its unique interaction with the NF-κB signaling pathway and its potential antiproliferative properties in various cell lines.

Our isolation process utilizes advanced chromatography to achieve high chromatographic purity, ensuring that the material is free from isomeric contaminants such as Isomitraphylline. This level of precision allows researchers to isolate the specific biological effects of the oxindole scaffold without interference from secondary alkaloids.

Research Applications include:

• Immunology: Investigation into cytokine regulation and anti-inflammatory mechanisms.

• Oncology Research: In-vitro studies regarding apoptosis induction in specific cell cultures.

• Analytical Chemistry: Use as a secondary alkaloid marker for full-spectrum botanical fingerprinting.